Hangzhou ROYAL Pharmaceutical Equipment Co.,Ltd  is mainly engaged in the R&D, Design, Produce and Trade of Pharmaceutical equipment, Chemical equipment, Laboratory Equipment and so on. We are located in Hangzhou city, Zhejiang Province. Neighboring Shanghai port, Ningbo port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudong Int’l Airport, the transportation and environment are excellent.

ROYAL PHARM Focus on:

█ TURN-KEY Project & Design for Pharmaceutical factory & Chemical factory & Laboratory.

█ Laboratory Equipment.

█ Glass Reactors, Enamel lined reactors, Stainless Steel reactors, PTFE coated reactors, PTFA (Halar) coated reactors and so on.

█ Distilled water production equipment

█ Centrifuge

█ Drying and Mixing Equipment

█ Packing Machinery

█ Auxiliary equipment such as: Disc type Condenser, Tube and shell Condenser, Cold Trap, Cooling and heating thermostat equipment, pumps, air compressor, filter, Grinding machine, Chromatograhic column and so on.

█ Packing Materials includes: the cold-form foil,tropical blister foil,low adsorption composite film,moisture and oxygen absorption packaging,liquid strip packaging,Oral liquid dispenser,High barrier Aclar,PVDC film,Alu-plastic film,Single recyclable film,High barrier evaporated film,High barrier coating film,wrap film,Vacuum body covering film,High barrier PP/PS/PET sheet,PTP alu foil,Strip foil,Drug substance bag,Moisture proof bottle, alu-plastic cover.

Our strongest machines include: Laboratory equipment, Glass Reactors, Enamel lined reactors, Stainless Steel reactors, PTFE coated reactors, PTFA (Halar) coated reactors, Distilled water production equipment, Centrifuge, Mixing machine, drying machine, grinding machine, Packing machine, Disc type Condenser, Tube and shell Condenser, Cold Trap, Cooling and heating thermostat equipment, pumps, air compressor, filter, Grinding machine, Chromatograhic column and so on.

Product Introduction:

The single-use freeze-drying tray is a new type of disposable freeze-dried plate developed based on the usage scenarios of traditional freeze dryers and freeze- drying processes. It is completely closed and sterile, and uses unique ePTFE membrane technology to prevent cross-contamination and flying out, and allows water vapor to be freely exchanged during the freeze-drying process.. According to the comprehensive needs of customers for customized production, to provide customers with high- quality products and professional services.

Application Usage:

Widely used in polypeptides, oligonucleotides, proteins, and API intermediates, polysaccharide and other products of the freeze-drying process research and development and large-scale production.

Main Specifications:

Superiority

50. Comprehensive supervision and control of manufacturing process and quality to ensure product stability and large-scale production.
50. Long-term contract and inventory of raw materials and related components to meet the supply guarantee and delivery reliability.

Requirements that the product meets

50. Insoluble particulate test (USP788)
50. In vitro cytotoxicity assay( USP 87 L-929 cells MTT method MTT method)
50. Acute toxicity test(USP 88)
50. Intradermal Irritation test (USP 88).
50. Muscle Implant Test (USP 88).
50. Sterility (USP 71).
50. Bacterial endotoxins test (USP 85).
50. Physical and chemical container test(USP 661).
50. Thermal conductivity of the carrier liquid membrane.
50. Vehicle compatibility.
50. Flatness test.

Operation Instructions

50. Place the freeze-drying tray on the plane.
50. Unscrew the valve cap from the injection port.
50. Inject an appropriate volume of product into the container according to the aseptic operation process: injection volume ≤1.8L.
50. Put the bonnet of the injection port back to the upper part of the injection port and tighten it by hand.
50. Place the freeze-drying tray in the freeze dryer for freeze-drying.

Product Collection

50. Take out the freeze-drying tray and turn it over.
50. With a sharp tool, cut the bottom of the flexible film along a corner, and be

careful not to cut into the body. The freeze-drying tray is held by the unscratched corner and tray, and the dry powder is poured into the collection bag or mixing device through the scratched corner. For the materials attached to the freeze- dried film can be slightly scraped with soft articles, do not use sharp tools to scrape the materials stuck to the film, so as not to shed the film

into the product.

50. According to the product characteristics and process requirements, the dry powder packaging or put into the next process

51.