- Product Details
Keywords
- Icotinib Hydrochloride
- Icotinib Hydrochloride manufacturer/supplier
- 1204313-51-8
Quick Details
- ProName: Icotinib Hydrochloride manufacturer/...
- CasNo: 1204313-51-8
- Molecular Formula: C22H22ClN3O4
- Appearance: white or off-white powder
- Application: Icotinib Hydrochloride CAS:1204313-51...
- DeliveryTime: in stock,shipment according to your re...
- PackAge: aluminum oil bag
- Port: shanghai
- ProductionCapacity: 1000 Metric Ton/Month
- Purity: 99%
- Storage: 0~20℃
- Transportation: by express,by sea, by air
- LimitNum: 1 Gram
- Related Substances: ≤1.0%
- Residue on Ignition: ≤0.1%
- Heavy Metal: ≤20ppm
- Valid Period: 2~3years
- Brand: Royall
- Grade Standard: Pharm grade
- Chemical Name: Icotinib Hydrochloride
- Molecular Weight: 427.88100
Superiority
We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO business service because of capacity limit, product cost limit or developing limit, plz feel free to contact us.
Besides, we could discuss the possible FDF distribution business. Hope to get the chance to discuss deeply.
Details
Hangzhou Jinlan Pharm-Drugs Technology Co., Limited is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudong Int’l Airport, the transportation and production environment are excellent.
We have established well market channels both domestically and overseas. Now JINLAN PHARMA is authorized by some Chinese chemical factories as universal agency and international area agency. Our products are exported to more than 100 countries and enjoy a well reputation, including Europe, USA, South America, India, south-east Asia and so on. Such as Canada, Germany, Spain, Australia, Russia, UAE, Estonia, Indonesia, Egypt, Pakistan and so on. Our machines with Excellent quality, Competitive price, Good after-service, are highly welcomed by our customers. We are pleased to know you and hope to be good friend and cooperator with you for our products. I am sure you will be satisfied with us.
Based on the philosophy of “Human-orient, Technical first, Quality product and High efficiency, Fact and Innovation”, JINLAN PHARMA highly welcome friends from all over the world to cooperate and get co-development.
Description
Icotinib Hydrochloride (BPI-2009H), or Icotinib, is a highly selective, first generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR-TKI). EGFR is an oncogenic driver and patients with somatic mutations, particularly an exon 19 deletion or exon 21 L858R mutation, within the tyrosine kinase domain have activating mutations that lead to unchecked cell proliferation. Overexpression of EGFR causes inappropriate activation of the anti-apoptotic Ras signaling pathway, found in many different types of cancer. Icotinib is a quinazoline derivative that binds reversibly to the ATP binding site of the EGFR protein, preventing completion of the signal transduction cascade.
Basic Info
Chemical Name |
Icotinib Hydrochloride |
Synonyms |
|
CAS No. |
1204313-51-8 |
Molecular Formula |
C22H22ClN3O4 |
Molecular Weight |
427.88100 |
PSA |
74.73000 |
LogP |
4.03410 |
Numbering system
UNII |
JTD32I0J83 |