- Product Details
Keywords
- Zebularine
- Zebularine manufacturer/supplier
- 3690-10-6
Quick Details
- ProName: Zebularine manufacturer/supplier
- CasNo: 3690-10-6
- Molecular Formula: C9H12N2O5
- Appearance: white or off-white powder
- Application: Zebularine CAS:3690-10-6 is used as A...
- DeliveryTime: in stock,shipment according to your re...
- PackAge: aluminum oil bag
- Port: shanghai
- ProductionCapacity: 1000 Metric Ton/Month
- Purity: 99%
- Storage: 0~20℃
- Transportation: by express,by sea, by air
- LimitNum: 1 Gram
- Related Substances: ≤1.0%
- Residue on Ignition: ≤0.1%
- Heavy Metal: ≤20ppm
- Valid Period: 2~3years
- Brand: Royall
- Grade Standard: Pharm grade
- Chemical Name: Zebularine
- Molecular Weight: 228.20200
Superiority
We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO business service because of capacity limit, product cost limit or developing limit, plz feel free to contact us.
Besides, we could discuss the possible FDF distribution business. Hope to get the chance to discuss deeply.
Details
Hangzhou Jinlan Pharm-Drugs Technology Co., Limited is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudong Int’l Airport, the transportation and production environment are excellent.
We have established well market channels both domestically and overseas. Now JINLAN PHARMA is authorized by some Chinese chemical factories as universal agency and international area agency. Our products are exported to more than 100 countries and enjoy a well reputation, including Europe, USA, South America, India, south-east Asia and so on. Such as Canada, Germany, Spain, Australia, Russia, UAE, Estonia, Indonesia, Egypt, Pakistan and so on. Our machines with Excellent quality, Competitive price, Good after-service, are highly welcomed by our customers. We are pleased to know you and hope to be good friend and cooperator with you for our products. I am sure you will be satisfied with us.
Based on the philosophy of “Human-orient, Technical first, Quality product and High efficiency, Fact and Innovation”, JINLAN PHARMA highly welcome friends from all over the world to cooperate and get co-development.
Description
Zebularine is a nucleoside analog of cytidine. It is a "transition state analog inhibitor of cytidine deaminase by binding to the active size as covalent hydrates. Also shown to inhibit DNA methylation and tumor growth both in vitro and in vivo."; In a small study of mice with a defective Adenomatous polyposis coli gene, oral administration of zebularine to males had no effect on the overall methylation of DNA or the number of polyps, but in females the average number of polyps was reduced from 58 to 1. It has therefore been suggested for drug use as a prototype of epigenetic therapy for cancer chemoprevention.
Zebularine (left) closely resembles cytidine (right), but lacks the 4'-amino group.
Basic Info
Chemical Name |
zebularine |
Synonyms |
4-Deoxyuridine;[14C]-Zebularine;Zebularine;1--D-Ribofuranosyl-2(1H)-pyrimidinone;4-Deoyuridine;Expand |
CAS No. |
3690-10-6 |
Molecular Formula |
C9H12N2O5 |
Molecular Weight |
228.20200 |
PSA |
104.81000 |
LogP |
-2.14520 |
Numbering system
UNII |
7A9Y5SX0GY |