Factory Supply 99.3% USP/EP/DMF CAS 910463-68-2 Sermaglutide Semaglutide CAS NO.910463-68-2

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Product Details

Keywords

Ozempic Rybelsus
Ozempic
Semaglutide (H-7894.0001)

Quick Details

ProName: Factory Supply 99.3% USP/EP/DMF CAS 91...
CasNo: 910463-68-2
Molecular Formula: C187H291N45O59
Appearance: white powder
Application: manage type 2 diabetes along with lif...
DeliveryTime: In the 5-15 working days
PackAge: 1g/bag
Port: Shanghai
ProductionCapacity: 1 Kilogram/Week
Purity: 99.3%
Storage: -20℃
Transportation: -20℃
LimitNum: 1 Gram
Related Substances: G06-IM60 ≤0.2% 0.08% G06-IM01 ≤0.2% 0...
Residue on Ignition: not tested
Heavy Metal: Sodium ion 1.0%~3.0% 2.1%
Valid Period: 2years
Appearance of solution: Colorless and clear liquid (C=10mg/ml)

Superiority

Hangzhou Jinlan Pharm-Drugs Technology Co. Ltd.(JL Pharm) is an advanced pharmaceutical corporation with a laboratory of 1200 square meters in Nanjing city, and cooperative GMP production plants in Beljing, Jiangsu, Zhejiang, Jiangxi, Chengdrand Shandong.We can provide both CDMO technology research and development services, and a ful range of laboratory R&D and production services for raw materials and pharmaceutical intermediates to globapharmaceutical companies during which synthetic route research and development, process reearch and development and optimization, scale-up production, domestic and foreign drug registration, and industrial equipment selection, automatic control system and technical process packages.

Details

Product Name:   Semaglutide

Synonyms:
Sermaglutide;Semaglutide impurity;
Sermaglutide USP/EP/BP;
semaglutide;
Sermaglutide CAS 910463 68 2;
Ozempic, Rybelsus;Ozempic;
Semaglutide (H-7894.0001)
CAS:   910463-68-2
MF:   C187H291N45O59
MW:   4113.57754
EINECS:   203-405-2
Product Categories:   GLP;PP;APIs;API;910463-68-2
Mol File:   910463-68-2.mol
Semaglutide Chemical Properties
storage temp.    Store at -20°C
solubility    DMSO:3mg/mL (0.73 mM)
InChIKey   DLSWIYLPEUIQAV-CCUURXOWSA-N
Uses   Semaglutide is used to manage type 2 diabetes along with lifestyle changes, such as dietary restrictions and increased physical activity. It also works by slowing the movement of food through the stomach and may decrease appetite and cause weight loss. There have been no published reports of hepatotoxicity attributed to semaglutide therapy.

Mechanism of action   Semaglutide is a glucagon-like peptide-1 receptor agonist. It increases the production of insulin, a hormone that lowers the blood sugar level. It also appears to enhance growth of β cells in the pancreas, which are the sites of insulin production. It also inhibits glucagon, which is a hormone that increases blood sugar. It additionally reduces food intake by lowering appetite and slows down digestion in the stomach. In this way it reduces body fat.

Amino acid analysis

Asp	0.9-1.1	0.9
Ser	2.1-3.9	2.6
Glu	4.5-5.5	5.1
Gly	3.6-4.4	4.0
His	0.9-1.1	1.0
Arg	1.8-2.2	2.1
Thr	1.8-2.2	2.0
Ala	2.7-3.3	3.0
Aib	0.7-1.3	1.1
Tyr	0.9-1.1	1.0
Val	1.8-2.2	2.2
Lys	0.9-1.1	1.0
Ile	0.9-1.1	1.0
Leu	1.8-2.2	2.1
Phe	1.8-2.2	2.1
Trp	Present	Present

Sodium ion	1.0%~3.0%		2.1%
Carbonate	≤0.50%		0.09%
Acetic acid	≤0.50%		N.D
Trifluoroacetic acid	≤0.25%		N.D.
Related Substance	G06-IM60	≤0.2%	0.08%
	G06-IM01	≤0.2%	0.07%
	G06-1M59	≤0.2%	0.06%
	G06-IM28	≤0.2%	0.08%
	G06-IM03	≤0.2%	0.07%
	Any other Unknown individual impurity	≤0.1%	N.D.
	Total Impurities	≤2.0%	0.29%
Residue solvents	Acetonitrile	≤410ppm	N.D.
	Triethylamine	≤5000ppm	17 ppm
	NN’-Diisopropylcarbodiimide	≤100ppm	N.D.
Polymer	≤0.5%		0.03%
Bacterial endotoxins	<10EU/mg		<10EU/mg
Microbial limit	Total aerobic microbial count	≤10²cfu/g	<10 cfu/g
	Total yeast and mold count	≤10²cfu/g	<10 cfu/g
	Escherichia coli	Absent	N.D.
Peptide content	≥80.0%		93.5%
Assay(on anhydrous and salt free substance basis)	95.0%-105.0%		99.3%