- Product Details
Keywords
- Dolasetron
- Dolasetron manufacturer/supplier
- 115956-12-2
Quick Details
- ProName: Dolasetron manufacturer/supplier
- CasNo: 115956-12-2
- Molecular Formula: C19H20N2O3
- Appearance: white or off-white powder
- Application: Dolasetron CAS:115956-12-2 is used a...
- DeliveryTime: in stock,shipment according to your re...
- PackAge: aluminum oil bag
- Port: shanghai
- ProductionCapacity: 1000 Metric Ton/Month
- Purity: 99%
- Storage: 0~20℃
- Transportation: by express,by sea, by air
- LimitNum: 1 Gram
- Related Substances: ≤1.0%
- Residue on Ignition: ≤0.1%
- Heavy Metal: ≤20ppm
- Valid Period: 2~3years
- Brand: Royall
- Grade Standard: Pharm grade
- Chemical Name: Dolasetron
- Molecular Weight: 324.37400
Superiority
We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO business service because of capacity limit, product cost limit or developing limit, plz feel free to contact us.
Besides, we could discuss the possible FDF distribution business. Hope to get the chance to discuss deeply.
Details
Hangzhou Jinlan Pharm-Drugs Technology Co., Limited is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudong Int’l Airport, the transportation and production environment are excellent.
We have established well market channels both domestically and overseas. Now JINLAN PHARMA is authorized by some Chinese chemical factories as universal agency and international area agency. Our products are exported to more than 100 countries and enjoy a well reputation, including Europe, USA, South America, India, south-east Asia and so on. Such as Canada, Germany, Spain, Australia, Russia, UAE, Estonia, Indonesia, Egypt, Pakistan and so on. Our machines with Excellent quality, Competitive price, Good after-service, are highly welcomed by our customers. We are pleased to know you and hope to be good friend and cooperator with you for our products. I am sure you will be satisfied with us.
Based on the philosophy of “Human-orient, Technical first, Quality product and High efficiency, Fact and Innovation”, JINLAN PHARMA highly welcome friends from all over the world to cooperate and get co-development.
Description
Dolasetron (trade name Anzemet) is a serotonin 5-HT3 receptor antagonist used to treat nausea and vomiting following chemotherapy. Its main effect is to reduce the activity of the vagus nerve, which is a nerve that activates the vomiting center in the medulla oblongata. It does not have much antiemetic effect when symptoms are due to motion sickness. This drug does not have any effect on dopamine receptors or muscarinic receptors.
Dolasetron breaks down slowly, staying in the body for a long time. One dose usually lasts 4 to 9 hours and is usually administered once or twice daily. This drug is removed from the body by the liver and kidneys.
Basic Info
Chemical Name |
Dolasetron |
Synonyms |
Dolasetronum [inn-latin];(2alpha,6alpha,8alpha,9abeta)-Octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl-1H-indole-3-carboxylate;(2a,6a,8a,9ab)-1H-Indole-3-carboxylic acid,octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester;1H-Indole-3-carboxylic acid,octahydro-3-oxo-2,6-methano-2H-quinolizin-8-yl ester,(2alpha,6alpha,8alpha,9abeta);Dolasetronum;Expand |
CAS No. |
115956-12-2 |
Molecular Formula |
C19H20N2O3 |
Molecular Weight |
324.37400 |
PSA |
62.40000 |
LogP |
2.45690 |
Numbering system
UNII |
82WI2L7Q6E |
Properties
Appearance & Physical State |
white powder |
Density |
1.37 g/cm3 |
Boiling Point |
535.1ºC at 760 mmHg |
Melting Point |
278ºC |
Flash Point |
277.4ºC |
Refractive Index |
1.76 |
Vapor Pressure |
4.08E-10mmHg at 25°C |
Safety Info
Safety Statements |
S26; S36 |
WGK Germany |
3 |
Risk Statements |
R36/37/38 |
Hazard Codes |
Xi |