- Product Details
Keywords
- Ibutilide Hemifumarate
- Ibutilide Hemifumarate manufacturer/supplier
- 122647-32-9
Quick Details
- ProName: Ibutilide Hemifumarate manufacturer/...
- CasNo: 122647-32-9
- Molecular Formula: C44H76N4O10S2
- Appearance: white or off-white powder
- Application: Ibutilide Hemifumarate CAS:122647-32-...
- DeliveryTime: in stock,shipment according to your re...
- PackAge: aluminum oil bag
- Port: shanghai
- ProductionCapacity: 1000 Metric Ton/Month
- Purity: 99%
- Storage: 0~20℃
- Transportation: by express,by sea, by air
- LimitNum: 1 Gram
- Related Substances: ≤1.0%
- Residue on Ignition: ≤0.1%
- Heavy Metal: ≤20ppm
- Valid Period: 2~3years
- Brand: Royall
- Grade Standard: Pharm grade
- Chemical Name: Ibutilide Hemifumarate
- Molecular Weight: 885.22500
Superiority
We can provide GMP validation service that complies with SFDA, FDA, WHO and EU EMPA.Excellent registration team could help us easlily to register our products in different countries.If you and your customer are interested in some products or need CMO business service because of capacity limit, product cost limit or developing limit, plz feel free to contact us.
Besides, we could discuss the possible FDF distribution business. Hope to get the chance to discuss deeply.
Details
Hangzhou Jinlan Pharm-Drugs Technology Co., Limited is located in Hangzhou, Zhejiang Province. Neighboring Ningbo port, Shanghai port, Hangzhou Xiaoshan Int’l Airport and Shanghai Pudong Int’l Airport, the transportation and production environment are excellent.
We have established well market channels both domestically and overseas. Now JINLAN PHARMA is authorized by some Chinese chemical factories as universal agency and international area agency. Our products are exported to more than 100 countries and enjoy a well reputation, including Europe, USA, South America, India, south-east Asia and so on. Such as Canada, Germany, Spain, Australia, Russia, UAE, Estonia, Indonesia, Egypt, Pakistan and so on. Our machines with Excellent quality, Competitive price, Good after-service, are highly welcomed by our customers. We are pleased to know you and hope to be good friend and cooperator with you for our products. I am sure you will be satisfied with us.
Based on the philosophy of “Human-orient, Technical first, Quality product and High efficiency, Fact and Innovation”, JINLAN PHARMA highly welcome friends from all over the world to cooperate and get co-development.
Description
Ibutilide is a Class III antiarrhythmic agent that is indicated for acute cardioconversion of atrial fibrillation and atrial flutter of a recent onset to sinus rhythm. It exerts its antiarrhythmic effect by induction of slow inward sodium current, which prolongs action potential and refractory period (physiology) of myocardial cells. Because of its Class III antiarrhythmic activity, there should not be concomitant administration of Class Ia and Class III agents.
Ibutilide is marketed as Corvert by Pfizer. Administration resulted in successful heart rhythm control in 31-44% of patients within 90 minutes, with sustained polymorphic ventricular tachycardia in 0.9-2.5% of patients. It appears to show better results in atrial flutter as compared to atrial fibrillation.
Basic Info
Chemical Name |
Ibutilide Hemifumarate |
Synonyms |
|
CAS No. |
122647-32-9 |
Molecular Formula |
C44H76N4O10S2 |
Molecular Weight |
885.22500 |
PSA |
230.64000 |
LogP |
10.34740 |
Numbering system
UNII |
9L5X4M5L6I |
Properties
Boiling Point |
522.4ºC at 760 mmHg |
Flash Point |
269.7ºC |
Vapor Pressure |
9.71E-12mmHg at 25°C |
Safety Info
Hazard Declaration |
H302 |
Signal Word |
Warning |
Symbol |
GHS07 |